Novel Molecular Type of Clostridium difficile in Neonatal Pigs, Western Australia

نویسندگان

  • Michele M. Squire
  • Glen P. Carter
  • Kate E. Mackin
  • Anjana Chakravorty
  • Torbjörn Norén
  • Briony Elliott
  • Dena Lyras
  • Thomas V. Riley
چکیده

Clostridium difficile causes neonatal enteritis in piglets; strains of PCR ribotype 078 are most commonly identified. We investigated C. difficile prevalence in piglets in Australia and isolated a novel strain with a unique pathogenicity locus. In a mouse infection model, this strain produced more weight loss than did a ribotype 078 strain.

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Nationwide surveillance study of Clostridium difficile in Australian neonatal pigs shows high prevalence and heterogeneity of PCR ribotypes.

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عنوان ژورنال:

دوره 19  شماره 

صفحات  -

تاریخ انتشار 2013